测定了28例未经治疗的糖尿病患者、19例治疗后得到良好控制的糖尿病患者及29例正常人血浆甘丙素、血糖、胰岛素、C肽水平。结果显示未经治疗的糖尿病患者甘丙素、血糖、胰岛素、C肽明显高于正常对照组,亦明显高于治疗后的糖尿病患者。甘丙素与血糖呈正相关,与胰岛素、C肽无明显相关,提示甘丙素在糖尿病发病和诊治过程中有重要意义,糖尿病亦存在高胰岛素血症。 Twenty-eight untreated patients with diabetes mellitus, 19 patients with well-controlled diabetes mellitus and 29 normal controls were enrolled in the study of plasma levels of galanin, glucose, insulin and C-peptide. The results showed that untreated patients with diabetes mellitus, blood glucose, insulin, C-peptide was significantly higher than the normal control group, also significantly higher than after treatment of diabetic patients. There was a positive correlation between galanin and blood glucose, but not with insulin and C-peptide, suggesting that galanin is important in the pathogenesis and diagnosis of diabetes and hyperinsulinemia in diabetes.