临床上破伤风抗毒素引起药物疹偶有发生,但出现严重过敏性休克,实属罕见,今报告1例,希望能引起广大同仁的关注。患者女,29岁,因脚外伤行残端修整术,术后给予脱敏肌注破伤风抗毒素1500个单位。注射第一针剂量1毫升后,患者肌注针眼处有轻微红肿,立即肌注非那根25毫克,约5分钟后,患者全射皮肤出现淡红色、大 Clinical tetanus antitoxin caused by drug rash occasionally, but there was a serious anaphylactic shock, it is rare, this report 1 case, hoping to arouse the attention of the majority of my colleagues. Female patient, 29 years old, due to foot injury stump repair surgery, desensitization after intramuscular injection of tetanus antitoxin 1500 units. Injection of the first dose of 1 ml, patients with intramuscular injection needle eye slight swelling, intramuscular injection of phenanthrene 25 mg, about 5 minutes later, the patient shot the skin appear pink, large