Objective:To investigate the reporting characteristics of case reports of acupuncture therapy with CAse Report (CARE) guidelines,and to explore the applicability of the guidelines for these case reports.Methods:Case reports published from January 1,2011 to December 31,2013,were identified by searching PubMed and the China Biomedicine Database by using MeSH terms.Screening and data extraction of case reports were conducted by two independent researchers.Assessments based on CARE guidelines and data analysis were conducted by using Excel 2003 and RevMan 5.0.Results:A total of 61 case reports published in 19 journals were identified,which involved 16 major types of diseases.Fifteen (24.6％) case reports declared no conflict of interests,and 5 (8.2％) reported funding sources.None of these case reports met all items of CARE guidelines,and only 6 subordinate items were fully reported among 50％ of the case reports.Subgroup analysis indicated that case reports published in English or those that did not have competing interests had higher reporting quality.Conclusions:The reporting quality of case reports of acupuncture therapy is rather low.The reason might be a lack of awareness among authors and the poor dissemination of information regarding CARE guidelines in China.More evaluation studies are needed to promote and improve adherence to CARE guidelines.Moreover,an extended version of CARE guidelines should be developed for cases reports of special interventions such as acupuncture or adverse events caused by interventions.