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目的:在以往研究的基础上世纪,进一步探讨早期先兆流产时CA125的变化规律,并对妊娠结局进行评估。方法:选择肾虚肝郁型早期先兆流产患者61例,随机分为中药治疗组31例和黄体酮对照组30例。动态检测血清CA125、定期B超检查及随访以知妊娠结局。结果:治疗后两组血清CA125水平均降低,与治疗前相比有显著性差异(P<0.05)。保胎成功组与保胎失败组患者CA125水平呈显著性差异(P<0.05)。两组治疗后CA125水平呈下降趋势,疗后第3周与疗前相比有统计学意义。结论:滋肾柔肝法治疗肾虚肝郁型早期先兆流产疗效显著,能降低血清CA125水平。动态监测血清CA125水平对评估早期先兆流产预后有一定的临床运用价值。
OBJECTIVE: In the last century, based on the previous studies, the variation of CA125 in early threatened abortion was further investigated, and the pregnancy outcome was evaluated. Methods: 61 cases of early threatened abortion with kidney deficiency and liver depression were randomly divided into 31 cases of Chinese medicine treatment group and 30 cases of progesterone control group. Dynamic detection of serum CA125, regular B-ultrasound and follow-up to know the pregnancy outcome. Results: The levels of serum CA125 in both groups decreased after treatment, which were significantly different from those before treatment (P <0.05). There was a significant difference (P <0.05) in the level of CA125 between the failed triage group and the failed failed triage group. The level of CA125 in both groups showed a decreasing trend after treatment, and the difference was statistically significant at the 3rd week after treatment. Conclusion: The method of nourishing the kidney and softening the liver to treat kidney deficiency and liver depression is effective in early threatened abortion, and can reduce the level of serum CA125. Dynamic monitoring of serum CA125 levels in the assessment of early threatened abortion prognosis of a certain clinical value.