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目的探讨新生儿Rh溶血病的疾病特征和诊疗经验,为临床诊治和改善患儿预后提供参考。方法对本院2015年1月~12月收治的12例新生儿Rh溶血病临床资料进行回顾性分析。结果 12例患儿主要是由Rh(D)(41.7%)、Rh(E)(33.3%)、Rh(E)联合Rh(c)(16.7%)、Rh(E)联合JKb(8.3%)引起的新生儿溶血病。4例患儿采用换血疗法,换血率33.3%,其余采用蓝光照射退黄,除1例中途转院外,其余患儿均治疗顺利。结论加强对新生儿Rh溶血病的认识,加大对产妇的血型筛查,及时诊断和治疗,降低该病的病死率和致残率。
Objective To investigate the disease characteristics and diagnosis and treatment experience of Rh hemolytic disease in neonates, and to provide reference for clinical diagnosis and treatment and prognosis improvement in children. Methods The clinical data of 12 cases of Rh hemolytic disease of neonates admitted from January 2015 to December 2015 in our hospital were analyzed retrospectively. RESULTS: Twelve cases were mainly composed of Rh (D) (41.7%), Rh (E) (33.3%), Rh (E) Cause of neonatal hemolytic disease. 4 cases of children with exchange of blood therapy, the exchange rate of 33.3%, the rest with blue light yellowing, except for 1 case of mid-transfer, the rest of the children were treated smoothly. Conclusion The understanding of Rh hemolytic disease in newborns should be strengthened and the blood type screening, maternal diagnosis and treatment should be increased to reduce the mortality and morbidity.