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目的:了解实施《抗菌药物临床应用指导原则》(以下简称为《指导原则》)后,我院2005年上、下半年抗菌药物的应用状况。方法:采用金额排序、用药频度(DDDs)排序及日均费用的变化进行统计分析。结果:实施《指导原则》后,下半年抗菌药物销售金额较上半年有所下降,DDDs排序前5名的均为口服抗菌药物,但个别品种用量偏大。结论:我院抗菌药物的使用在选择给药途径上基本合理。但在固定的人群中,部分药品用量偏大,存在一定的不合理性。加强宣传滥用抗菌药物的危害,合理使用抗菌药物,减少或减缓耐药菌,尤其是多重耐药菌的产生。
OBJECTIVE: To understand the application status of antimicrobials in the first and second half of 2005 in our hospital after implementing the Guiding Principles of Clinical Application of Antibacterials (hereinafter referred to as Guiding Principles). Methods: Statistical analysis was carried out using the order of the amount, the frequency of medication (DDDs) and the daily average cost. Results: After the implementation of the Guiding Principles, the sales of antimicrobial drugs in the second half of the year declined from the first half of the year. The top five DDDs were all oral antimicrobial drugs, but the consumption of individual varieties was relatively large. Conclusion: The use of antibacterials in our hospital is basically reasonable in choosing the route of administration. However, in a fixed population, some drugs are too large, there is a certain degree of irrationality. Strengthen the publicity on the abuse of antimicrobial drugs, use rational use of antimicrobial drugs, and reduce or slow down the generation of drug resistant bacteria, especially multidrug resistant bacteria.