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目的:探讨血管紧张素转换酶抑制剂(ACEI)在飞行员高血压患者群体中服用的安全性和有效性.方法:入选60例有高血压病的飞行员患者,每日口服盐酸贝那普利10mg,随访6个月,观察降压效果及不良反应.结果:治疗前收缩压平均为(149±4)mmHg,治疗后收缩压平均为(129±4)mmHg,两者比较有显著性差异;治疗前舒张压(88±3)mmHg,治疗后舒张压(78±3)mmHg,两者比较无显著性差异.其中2例出现干咳不良反应,无其他不良反应.结论:飞行员高血压病患者,选择血管紧张素转换酶抑制剂盐酸贝那普利长期服用是安全有效的.
Objective: To investigate the safety and efficacy of angiotensin converting enzyme inhibitor (ACEI) in the population of pilot hypertensive patients.Methods: Sixty patients with hypertensive pilots were enrolled in this study. The daily oral administration of benazepril hydrochloride 10mg , Followed up for 6 months, the antihypertensive effects and adverse reactions were observed.Results: The average systolic blood pressure before treatment was (149 ± 4) mmHg, the mean systolic blood pressure after treatment was (129 ± 4) mmHg, with significant difference between the two groups The pre-treatment diastolic blood pressure (88 ± 3) mmHg, post-treatment diastolic blood pressure (78 ± 3) mmHg, there was no significant difference between the two, of which 2 cases of adverse reactions of dry cough, no other adverse reactions.Conclusion: Pilots hypertensive patients , Long-term use of angiotensin converting enzyme inhibitor benazepril hydrochloride is safe and effective.