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目的：探讨丁螺环酮联合高压静电治疗广泛性焦虑症的临床疗效和安全性。方法将60例广泛性焦虑症患者随机分为两组，每组30例，两组均口服丁螺环酮治疗，研究组联合高压静电治疗，观察6周。治疗前后采用汉密顿焦虑量表评定临床疗效，并随时记录治疗过程中出现的不良反应。结果治疗6周末研究组显效率为70．0％、有效率为100％，对照组分别为43．3％、86．7％，研究组显效率、有效率均显著高于对照组（χ2＝4．34、4．28，P＜0．05）；治疗过程中两组均未出现严重不良反应。结论丁螺环酮联合高压静电治疗广泛性焦虑症起效快，疗效显著，安全性高，显著优于单用药物治疗。“,”Objective To explore the efficacy and safety of buspirone combined with high voltage static therapy (HVST) for generalized anxiety disorder (GAD) .Methods Sixty GAD patients were randomly divided into two groups of 30 ones each ,both groups took orally buspirone ,and research group was plus HVST for 6 weeks .Clinical efficacies were assessed with the Hamilton Anxiety Scale (HAMA) before and after treatment and adverse reactions recorded at any time during treatment .Results At the end of the 6th week obvious effective and effective rate were respectively 70 .0% and 100% in research and 43 .3%and 86 .7% in control group ,the former was significantly higher than the latter (χ2 =4 .34 ,4 .28 , P<0 .05);both groups didn’t show severe adverse reactions during treatment .Conclusion Buspirone plus HVST takes effect more rapidly and has an evident effect and higher safety compared with single-use medi-cation in GAD .