脱氧精胍菌素是抗肿瘤抗生素精胍菌素抗瘤作用最强的衍生物,两者具有与环孢菌素 A 相似或更强的抑制多种移植排斥反应作用,能有效地延长移植物存活时间,也表现了很好的预防和治疗动物实验性自身免疫病的作用。它优于环孢菌素,当器官移植出现排斥症状和自身免疫病形成后仍有很好治疗作用,在临床肾移植病人的冲击治疗中取得较好疗效。 Deoxyspergualin is the antitumor antibiotic spergualin the strongest antitumor derivatives, both with cyclosporin A or similar inhibition of multiple transplant rejection, which can effectively extend the graft Survival time, but also showed a good role in the prevention and treatment of experimental autoimmune diseases in animals. It is superior to cyclosporin and has good therapeutic effect after the rejection of organ transplant and the formation of autoimmune diseases. It has achieved good effect in the treatment of patients with clinical renal transplant.