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目的探讨术中自体血液回输对血液流变学及生化指标的影响。方法选择出血量＞500ml手术患者共30例，ASAⅠ或Ⅱ级，随机观察组与对照组各15例，观察组分别于手术前和回输完自体血液手术后24h抽取股动脉和股静脉血液；对照组分别于手术前和异体血液输完后24 h抽血，即刻送检血液流变学和生化指标分析。结果与麻醉前比较，输血后对照组红细胞沉降率（ ESR）加快，红细胞压积降低；观察组血沉加快，而红细胞压积变化差异无显著性；术后检测的各项指标除谷转氨酶（AST）变化不明显，其他的变化趋势均优于对照组（P＜0．05）。结论自身输血对机体整体血液流变学及部分生化指标特性不会产生明显的负面影响，临床证明其安全有效，可作为输血技术的有效补充。“,”Objective To investigate the effect of autotransfusion on hemorheology and biochemical indcators .Meth-ods More than 500ml blood loss in patients with atotal of 30cases of surgery,ASAⅠor classⅡ,were randomly divided into two groups:15 cases of the observation group were insurgery and before the end of autotransfusion of blood taken from 24h after the operation femoral artery and femoral vein blood;15cases in the control group,respectively, Allogeneic blood before surgery and 24h after blood transfusion, blood rheology immediate inspection and biochemical analysis of the indicators.Results Compared with the pre-anesthesia, after blood transfuion in the control group to speed up sedimentation rate, lower hemato-crit;observer Group to speed up sedimentation rate, and hematocrit changes were not significantly different;after the detection of targets in addition to alanine aminotransferase ( AST)did not change significantly.Other trends are similar to the control group.Conclusion Autotransfusion has no asverse effect on systemic safety and effectiveness by Clinical and can be used as an effective complement of blood transfusion technology .