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[目的]对某中生菌素进行毒理学安全性评价,了解其毒性。[方法]根据《农药登记毒理学试验方法》,分别利用大鼠和新西兰白兔对该样品进行急性经口毒性试验、急性经皮毒性试验、急性皮肤刺激试验和急性眼刺激试验。[结果]该样品大鼠急性经口毒性试验和急性经皮毒性试验结果均表明该样品属低毒,急性皮肤刺激试验结果为无刺激性。急性眼刺激试验结果为轻刺激性。[结论]该中生菌素具有一定毒性,要更全面了解其安全性尚待进一步研究。
[Objective] To evaluate the toxicological safety of a certain mycotoxin and understand its toxicity. [Method] Acute oral toxicity test, acute dermal toxicity test, acute skin irritation test and acute eye irritation test were conducted on the samples using rat and New Zealand white rabbits respectively according to “Toxicological Tests for Pesticide Registration”. [Result] The results of acute oral toxicity test and acute dermal toxicity test of this sample showed that the sample was of low toxicity and the result of acute skin irritation test was non-irritating. Acute eye irritation test results for light irritation. [Conclusion] The mycotoxin has a certain toxicity, to be more fully understand its safety remains to be further studied.