Discovery of Novel Irreversible HER2 Inhibitors for Breast Cancer Treatment

来源 :生物医学工程(英文) | 被引量 : 0次 | 上传用户：www_acafa_com

【摘要】

：

It has been widely known that human epidermal growth factor receptor 2 (HER2) inhibitors exhibit distinct antitumor responses against HER2-positive breast cance

【作者】

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Jhih-Yan Tang Yih Ho Chun-Yi C

【机构】

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DepartmentofChemicalEngineeringandBiotechnology,SchoolofPharmacy,InstituteofBiochemicalandBiomedical

【出处】

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生物医学工程(英文)

【发表日期】

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2019年4期

【关键词】

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BREAST Cancer IRREVERSIBLE HER2 INHIBITORS STRUCTURE-BASED PHARMACOPHORE Modelin

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It has been widely known that human epidermal growth factor receptor 2 (HER2) inhibitors exhibit distinct antitumor responses against HER2-positive breast cancer. To date, Lapatinib (Tykerb®) has been approved by the U.S. Food and Drug Administra

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