论文部分内容阅读
晚期恶性淋巴瘤患者病情严重,浸润范围广泛,经多次化疗而效果不佳。我院自1991年11月至今对3例晚期恶性淋巴瘤进行自体骨髓移植加大剂量化疗,现报告如下。临床资料3例均经病理组织学确诊。1男,2女。年龄分别为48、28、62岁。2例非何杰金氏病淋巴瘤T 细胞型,1例何杰金氏病混合细胞型。病期2例为Ⅳ期,1例为Ⅲ期。1例经4个月多种方案化疗,未能控制病情发展,肝、脾、淋巴结及两肺弥漫性浸润、高热、气急、平卧时需吸氧,一般情况极差,多次血气分析,氧分压<60mmHg。1例经9个疗程化疗,纵膈淋巴结仍然肿大。另1例经2个疗程化疗未完全缓解(CR)。
Patients with advanced malignant lymphoma in a serious condition, a wide range of infiltration, after multiple chemotherapy and ineffective. Our hospital since November 1991 to date three cases of advanced malignant lymphoma autologous bone marrow transplantation and high dose chemotherapy, are as follows. 3 cases of clinical data were confirmed by histopathology. 1 male, 2 female. The ages were 48,28,62 years old. 2 cases of non-Hodgkin’s disease lymphoma T cell type, 1 case of Hodgkin’s disease mixed cell type. 2 cases of disease stage Ⅳ, 1 cases of stage Ⅲ. 1 case after 4 months of various programs of chemotherapy, failed to control the progression of the disease, liver, spleen, lymph nodes and diffuse infiltration of both lungs, fever, shortness of breath, supine oxygen, the general situation is poor, multiple blood gas analysis, Oxygen partial pressure <60mmHg. One case after 9 courses of chemotherapy, mediastinal lymph nodes still swollen. Another case of 2 courses of chemotherapy did not completely relieve (CR).