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目的对心血管病危险因素进行诊断试验,探讨其对冠心病的诊断价值。方法于2008年10月-2009年12月对山东大学齐鲁医院行冠状动脉造影术的812例患者,进行心血管病危险因素及冠脉造影结果进行分析。结果根据冠脉造影结果确诊冠心病662例,将患者分为冠心病组与非冠心病组,应用Logistics回归分析结果表明,男性、年龄、高血压(HT)、糖尿病(DM)、高密度脂蛋白胆固醇(HDL-C)是冠心病的主要危险因素;冠脉造影结果表明,这5个危险因素对冠心病诊断的敏感性为95.47%(632/662),特异性为64.00%(96/150),阳性预测值为92.13%(632/686),阴性预测值为76.19%(96/126)。结论男性、年龄、高血压、糖尿病、低HDL-C是冠心病的主要危险因素,其联合应用对冠心病有较高的诊断价值。
Objective To diagnose the risk factors of cardiovascular disease and investigate its diagnostic value on coronary heart disease. Methods From October 2008 to December 2009, 812 patients who underwent coronary angiography at Qilu Hospital of Shandong University were enrolled in the study. The risk factors of cardiovascular disease and coronary angiography were analyzed. Results 662 CHD patients were confirmed according to coronary angiography results. Patients were divided into coronary heart disease group and non-coronary heart disease group. Logistics regression analysis showed that male, age, hypertension (HT), diabetes mellitus (DM) The results of coronary angiography showed that the sensitivity of these five risk factors to the diagnosis of coronary heart disease was 95.47% (632/662) and the specificity was 64.00% (96 / 150), the positive predictive value was 92.13% (632/686), the negative predictive value was 76.19% (96/126). Conclusions Male, age, hypertension, diabetes and low HDL-C are the main risk factors of coronary heart disease. The combination of them has a high diagnostic value for coronary heart disease.