近年来我们收治原发性胃肠道恶性淋巴瘤12例,男7例,女5例,年龄17～64岁,平均38.5岁。胃3例,肠8例,胃肠1例,均经病理证实;除1例为何杰金氏型外,余9例为非何杰金氏型(2例未分型)。主要临床表现有腹痛、消瘦、腹部包块、呕吐、黑便等。临床诊断本病仅2例,经胃镜诊断1例(1/3),经X线诊断3例(3/8),其余6例均误诊为其它疾病。本组除2例Ⅰ期患者行根治性手术切除外,余均因晚期失去手术时机行姑息手术及化疗;现随访到8例,除1例健在外,余均在半年内死亡。原发性胃肠道恶性淋巴瘤,特别是非何杰金氏型,常同时侵犯淋巴结以外的淋巴组织,诊断 In recent years, we treated 12 cases of primary gastrointestinal malignant lymphoma, 7 males and 5 females, aged 17 to 64 years, with an average of 38.5 years. 3 cases of stomach, 8 cases of intestine, and 1 case of gastrointestinal tract were confirmed by pathology. Except for 1 case of Jagger type, 9 cases were non-Hodgkin type (2 cases without classification). The main clinical manifestations are abdominal pain, weight loss, abdominal mass, vomiting, black stool and so on. There were only 2 cases of clinical diagnosis of the disease, 1 case (1/3) diagnosed by gastroscopy, 3 cases (3/8) diagnosed by X-ray, and the remaining 6 cases were misdiagnosed as other diseases. In this group, except for 2 patients with stage I who underwent radical surgical resection, Yu was due to late loss of surgical time for palliative surgery and chemotherapy; 8 patients were followed up, and except for 1 patient who was still alive, all of them died within six months. Primary gastrointestinal lymphomas, particularly non-Hodgkin’s, often invade lymphoid tissues other than lymph nodes and diagnose