论文部分内容阅读
对抑郁症发病机制的解释主要以中枢神经系统单胺类递质的功能失调为主,然而新的研究表明除单胺类神经递质外,谷氨酸等神经递质也扮演了非常重要的角色。该文就谷氨酸循环的生理特点及其在抑郁症中可能的病理生理作用及各类针对谷氨酸异常抗抑郁药物的治疗进展进行综述。
The explanation for the pathogenesis of depression mainly focuses on the dysfunction of monoamine neurotransmitters in the central nervous system. However, new studies have shown that neurotransmitters such as glutamate play a very important role in addition to monoamine neurotransmitters Character. This article reviews the physiological characteristics of glutamate cycle and its possible role in the pathophysiology of depression and the progress of various anti-depressant drugs against glutamate.