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目的评价高强度聚焦超声联合化放疗与单纯化放疗治疗大肠癌肝转移的近期临床疗效。方法大肠癌肝转移93例,48例采用HIFU联合化放疗(HIFU组),与45例单纯采用化放疗(对照组)对比,评价两组的近期临床疗效。结果 HIFU组总有效率56.3%(27/48),对照组总有效率35.6%(16/45),两组有效率差异有显著性(P<0.05)。结论 HIFU联合化放疗治疗大肠癌肝转移近期有效率明显优于单纯化放疗。
Objective To evaluate the short-term clinical efficacy of high intensity focused ultrasound combined with chemoradiotherapy and simple radiotherapy in the treatment of liver metastasis of colorectal cancer. Methods 93 patients with liver metastasis of colorectal carcinoma were treated with HIFU combined with radiotherapy (HIFU). Forty-five patients were treated with chemoradiotherapy alone (control group). The clinical efficacy of the two groups was evaluated. Results The total effective rate was 56.3% (27/48) in HIFU group and 35.6% (16/45) in control group, with significant difference (P <0.05). Conclusion The recent effective rate of HIFU combined with chemoradiotherapy in the treatment of liver metastasis of colorectal cancer is obviously better than that of simple radiotherapy.