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1971年3月~1986年8月收治51例头颈部腺样囊性癌。其中单纯放疗9例,术后复发再放疗14例,术后补充放疗16例,术前放疗4例,单纯手术8例。照射剂量30~80Gy/3~8周。5年、10年和15年生存率分别是51.0%(26/51)、40.9%(9/22)和36.4%(4/11),5年、10年和15年无病生存率分别是39.2%(20/51)、31.8%(7/22)和36.4%(4/11)。单纯放疗及术后复发再放疗共23例中放疗后完全消退3例,消退≥50%10例,消退<50%10例,年生存率为47.8%(11/23),有较好的姑息作用。术后补充放疗5年生存率68.7%(11/16),疗效肯定应予提倡。单纯放疗剂量应70~80Gy/7~8周甚至更高。颈部淋巴结不做预防照射后转移率10.3%(3/29)。不主张预防照射颈部。
From March 1971 to August 1986, 51 cases of head and neck adenoid cystic carcinoma were treated. Among them, 9 cases were radiotherapy alone, 14 cases were recurrence after radiotherapy, 16 cases were postoperative radiotherapy, 4 cases were preoperative radiotherapy, and 8 cases were simple surgery. Irradiation dose 30 ~ 80Gy / 3 ~ 8 weeks. The 5-year, 10-year, and 15-year survival rates were 51.0% (26/51), 40.9% (9/22), and 36.4% (4/11), respectively. The 5-year, 10-year, and 15-year disease-free survival rates were 39.2% (20/51), 31.8% (7/22) and 36.4% (4/11). After radiotherapy and postoperative recurrence and re-radiotherapy, 23 patients completely dissipated after radiotherapy in 3 cases, ≥ 50% resolved in 10 cases, and remission was <50% in 10 cases. The annual survival rate was 47.8% (11/23), and there was better palliative care. effect. The 5-year survival rate after radiotherapy supplementation was 68.7% (11/16). The curative effect should definitely be promoted. The dose of radiotherapy alone should be 70 ~ 80Gy / 7 ~ 8 weeks or even higher. The metastatic rate of cervical lymph nodes without preventive irradiation was 10.3% (3/29). Does not advocate the prevention of irradiation of the neck.