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【目的】探讨出生体重与儿童期超重肥胖的关系,为预防和减少儿童肥胖的发生提供科学依据。【方法】采用历史性队列研究方法,随机抽取无锡地区1 435对巨大儿和正常出生体重儿作为研究对象,通过问卷调查和体格检查随访收集所有研究对象与肥胖相关的资料,分析出生体重与儿童期超重肥胖的关系。【结果】巨大儿中超重和肥胖检出率分别为13.10%和2.86%,正常儿中超重和肥胖检出率分别为9.69%和1.61%;巨大儿超重和肥胖检出率高于正常儿(P<0.01);巨大儿与正常儿相比,发生超重和肥胖的RR值分别为1.35和1.78,AR值分别为3.41%和1.26%。经趋势χ2检验发现,随着出生体重的增加,超重和肥胖率均增加(P<0.01),发生超重和肥胖的RR值和AR值也随之增加;经多元线性回归分析表明,出生体重、性别、父亲和母亲的BMI以及喜欢吃油炸食品可能为儿童期BMI的影响因素。【结论】出生体重与儿童期肥胖有关,预防肥胖应从胎儿期开始。
【Objective】 To explore the relationship between birth weight and childhood overweight and obesity, and to provide a scientific basis for prevention and reduction of childhood obesity. 【Methods】 A total of 1 435 children with macrosomia and normal birth weight in Wuxi were selected randomly from the historical cohort study. All subjects were ob- served with obesity-related data by questionnaire survey and physical examination. The relationship between birth weight and children Overweight and obesity in the relationship. 【Results】 The detection rates of overweight and obesity in giant children were 13.10% and 2.86% respectively. The detection rates of overweight and obesity in normal children were 9.69% and 1.61% respectively. The detection rate of overweight and obesity in giant children was higher than that of normal children P <0.01). Compared with normal children, the average RR of overweight and obesity was 1.35 and 1.78 respectively, and the AR values were 3.41% and 1.26% respectively. The results of Chi-square test showed that with the increase of birth weight, the overweight and obesity rates increased (P <0.01), and the RR and AR values of overweight and obesity increased. The multiple linear regression analysis showed that birth weight, Gender, father’s and mother’s BMI, and factors that may affect deep-sea BMI like eating fried foods. 【Conclusion】 Birth weight is related to childhood obesity, and prevention of obesity should start from fetal stage.