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受试者有:A组43例原发性高血压(收缩压≥160mmHg和/或舒张压≥95mmHg),B组16例临界高血压,C组17例正常血压(≤140/90mmHg)。A组各例均无心力衰竭、肾功能衰竭或代谢疾病;试验前从未服用降压药物或者试验前至少2周降压药物已从体内清除;其中4例因高血压急症而入院。(A、B和C)三组的年龄(53±9、49±11和48±10岁)、性别(男性56.8％、50.0％和52.0％)和血清肌酐浓度(1.0±0.3、0.9±0.3和0.9±0.3mg/dl)均无显著差别。三组平均动脉压分别为127.0±18.2、109.6±3.7和94.1±7.1mmHg;血浆心钠素水平
Subjects included 43 patients with essential hypertension (systolic blood pressure ≥ 160 mmHg and / or diastolic blood pressure ≥ 95 mmHg) in group A, 16 patients with critical hypertension in group B and 17 patients with normal blood pressure (≤ 140/90 mmHg) in group C. None of the patients in group A had heart failure, renal failure, or metabolic disease. Hypotensive drugs were never taken before the test or antihypertensive drugs were cleared from the body at least 2 weeks before the test. Four of the patients were admitted to hospital due to an emergency of hypertension. (53 ± 9,49 ± 11 and 48 ± 10 years), gender (men 56.8%, 50.0% and 52.0%) and serum creatinine concentrations (1.0 ± 0.3,0.9 ± 0.3) in the three groups (A, B and C) And 0.9 ± 0.3 mg / dl). The mean arterial pressure in the three groups were 127.0 ± 18.2,109.6 ± 3.7 and 94.1 ± 7.1mmHg, respectively. Plasma atrial natriuretic peptide