目的:探讨散结镇痛胶囊对子宫内膜异位症腹腔术后患者的疗效及血清CA125的影响。方法:160例子宫内膜异位症患者按照随机分组法分为治疗组和对照组各80例。两组均采用腹腔手术治疗。治疗组采用中药散结镇痛胶囊治疗,对照组采用西药治疗。两组疗程均为4周。对比分析两组疗效、血清CA125水平、子宫动脉血流频谱参数、不良反应及复发情况。结果:治疗组总有效率(96.25%)显著高于对照组(82.50%)(P<0.05);两组血清CA125水平治疗后较治疗前显著减少(P<0.05);治疗组血清CA125水平显著低于对照组(P<0.05);两组RI、PI、S/D治疗后较治疗前显著减少(P<0.05);两组RI和S/D治疗后比较无统计学差异(P>0.05);治疗组PI治疗后显著低于对照组(P<0.05);两组不良反应发生率比较无统计学差异(P>0.05);两组复发率比较无统计学差异(P>0.05)。结论:散结镇痛胶囊对子宫内膜异位症腹腔术后患者的疗效显著,可明显降低血清CA125水平,具有重要研究意义。 Objective: To investigate the efficacy of Sanjiezhitong Capsule on patients with endometriosis after abdominal surgery and the effect of serum CA125. Methods: 160 patients with endometriosis were randomly divided into treatment group and control group of 80 cases. Both groups were treated with abdominal surgery. The treatment group was treated with Sanjie Analgesic Capsule, while the control group was treated with western medicine. Two courses of treatment were 4 weeks. The curative effect, serum CA125 level, spectral parameters of uterine artery blood flow, adverse reactions and recurrence were compared between the two groups. Results: The total effective rate (96.25%) in the treatment group was significantly higher than that in the control group (82.50%) (P <0.05). Serum CA125 levels in both groups were significantly decreased after treatment (P <0.05) (P <0.05). The RI, PI and S / D after treatment in both groups were significantly lower than those before treatment (P <0.05). There was no significant difference between the two groups after RI and S / D treatment (P> 0.05 ). The PI in the treatment group was significantly lower than that in the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). There was no significant difference in relapse rate between the two groups (P> 0.05). Conclusion: Sanjiezhitong Capsule has significant curative effect on patients with endometriosis after abdominal surgery, and can significantly reduce serum CA125 level, which has important research significance.