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氨基甙类抗生素对中老年病人肾功能的影响一直是临床医生所关心的问题。我们选取目前广泛使用的丁胺卡那霉素(简称丁卡),监测病人用药前后尿白蛋白(ALB)、尿N·乙酰-β-D-氨基葡萄糖苷酶(NAG)、尿β_2-微球蛋白(β_2-M)的变化,观察丁卡在常规剂量下对老年病人肾功能的影响,以了解其用药安全性。
The effect of aminoglycosides on renal function in middle-aged and elderly patients has always been a concern for clinicians. We select the currently widely used amikacin (Ding card), monitoring patients before and after treatment of urine albumin (ALB), urine N · acetyl-β-D-glucosaminidase (NAG) Globulin (β_2-M) changes in the observed Dinka in the conventional dose of renal function in elderly patients to understand its drug safety.