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为了探索~(131)碘的合适剂量,提高1次治愈率,减低甲低率,我们就1977—1982年经随访的140例进行分析。临床资料一、性别和年龄:男25例,女115例,男:女为1:4.6。年龄从27岁~62岁,其中以30~50岁为多,占73.6%,50岁以上占26.4%。二、病期:病期半年~15年。三、类型及甲状腺肿大程度:弥漫性甲状腺肿121例,结节性甲状腺肿11例,甲亢术后复发者8例;根据触诊法和甲状腺扫描估计甲状腺重量:Ⅰ°(30~40g)65例,占46.42%;Ⅱ°(50~60g)56例,占40%;Ⅲ°(70~80g)19例,占13.57%。服~(131)碘次数:1次108例,占77.1%;2次32例,占22.8%。第一次服~(131)碘剂量按每克甲状腺组织给予60μc的有131例,占93.57%,按每克甲状腺组织给予65μc的有9例,占6.43%,首次剂量范围2~10mc,平均剂量为4.5mc。
In order to explore the appropriate doses of ~ (131) iodine, increase the cure rate and reduce the rate of hypothyroidism, we analyzed 140 follow-up cases from 1977 to 1982. Clinical data A, gender and age: male 25 cases, female 115 cases, male: female 1: 4.6. The age ranged from 27 to 62 years, of which 30 to 50 years old, accounting for 73.6%, over 50 accounted for 26.4%. Second, the duration of disease: six months to 15 years. Third, the type and degree of goiter: diffuse goiter in 121 cases, nodular goiter in 11 cases, hyperthyroidism recurrence in 8 cases; according to palpation and thyroid scan estimated thyroid weight: Ⅰ ° (30 ~ 40g) 65 cases accounted for 46.42%; Ⅱ ° (50 ~ 60g) 56 cases, accounting for 40%; Ⅲ ° (70 ~ 80g) 19 cases, accounting for 13.57%. Serve ~ (131) iodine times: once a case of 108 cases, accounting for 77.1%; two 32 cases, accounting for 22.8%. The first dose of ~ (131) iodine per gram of thyroid tissue was given 60μc in 131 cases, accounting for 93.57%, per gram of thyroid tissue was given 65μc in 9 cases, accounting for 6.43%, the first dose range of 2 ~ 10mc, mean The dose is 4.5mc.