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乳腺癌属于激素依赖性肿瘤,它的生长和发展引起病人机体内分泌的变化,这种变化特别表现在年龄上。内分泌状态的改变对免疫应答产生不良影响,从而使其在肿瘤发展过程中起极大的作用。近年来青年乳腺癌患者的比重有不断增加的趋势。作者提请研究机构对青年乳腺癌患者的内分泌调节系统和体液免疫的关系予以特殊的注意。 研究对象为青年(28～35岁)和中年(36～45岁)Ⅰ-Ⅲ期乳腺癌患者各26名,与病人年龄相当的健康妇女50名。 研究方法:在治疗前月经周期(28～30天)的第5～7天和第22～25天采集空腹血
Breast cancer is a hormone-dependent tumor. Its growth and development cause changes in the patient’s endocrine system. This change is particularly manifested in age. Changes in the endocrine state have an adverse effect on the immune response, thereby making it play a significant role in the development of the tumor. In recent years, the proportion of young breast cancer patients has been increasing. The authors drew particular attention to the relationship between the endocrine regulatory system and humoral immunity in young breast cancer patients. The study included 26 young people (age 28 to 35 years old) and middle-aged (36 to 45 years old) stage I-III breast cancer patients, and 50 healthy women of similar age. Methods: Fasting blood was collected on days 5 to 7 and 22 to 25 of the menstrual cycle (28 to 30 days) before treatment