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小贴士造血干细胞移植是治疗白血病、重度再生障碍性贫血病、重症免疫缺陷病等多种疾病的有效手段。据相关资料统计,我国每年有100万患者需要进行造血干细胞移植,仅白血病患者每年就新增4万余人。造血干细胞移植成功的关键在于患者与捐献者之间的HLA,即人类白细胞组织相溶性抗原分型相合。由于非血缘关系常见的HLA型别中,相合率只有几十万分之一。患者的生命要延续,只能在数以万计,甚至数十万计的志愿者中寻找配型相合的志愿者。
Tips Hematopoietic stem cell transplantation is an effective treatment for many diseases such as leukemia, severe aplastic anemia and severe immune deficiency disease. According to relevant statistics, there are 1 million patients in our country who need hematopoietic stem cell transplantation each year, and only 40,000 people are newly added to leukemia patients each year. The key to the success of hematopoietic stem cell transplantation lies in the HLA matching between the patient and the donor, ie, human leucocyte tissue-compatible antigen typing. Due to the non-blood type common HLA type, the coincidence rate of only one hundred millionth. The patient’s life should be continued, only in the tens of thousands, or even hundreds of thousands of volunteers looking for matching volunteers.