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目的探讨间断无创正压通气治疗慢性阻塞性肺疾病急性加重期(AECOPD)的疗效。方法将我院自2009年2月至2010年2月收治的50例AECOPD患者,随机分为观察组和对照组,每组25例,对照组采用常规治疗,观察组在对照组基础上采用间断无创正压通气,比较两组患者治疗后肺功能、动脉血氧分压及动脉二氧化碳分压及疗效。结果观察组患者中显效20例,有效2例,总有效率为88.0%,显著高于对照组的72.0%,P<0.05。且观察组的肺功能、动脉血氧分压及动脉二氧化碳分压均较对照组有明显改善,P<0.05。结论无创通气可迅速改善肺部气体交换,缓解AECOPD患者的缺氧状况,增强肺功能,提高患者的生活质量。
Objective To investigate the curative effect of intermittent non-invasive positive pressure ventilation on acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods Fifty patients with AECOPD admitted to our hospital from February 2009 to February 2010 were randomly divided into observation group and control group, with 25 cases in each group. The control group was treated with conventional therapy. The observation group was treated with intermittent Non-invasive positive pressure ventilation, pulmonary function after treatment, arterial partial pressure of oxygen and arterial carbon dioxide partial pressure and efficacy. Results In the observation group, 20 cases were markedly effective and 2 cases were effective. The total effective rate was 88.0%, which was significantly higher than that of the control group (72.0%, P <0.05). The pulmonary function, arterial partial pressure of oxygen and arterial partial pressure of carbon dioxide in the observation group were significantly improved compared with the control group (P <0.05). Conclusion Non-invasive ventilation can rapidly improve the gas exchange in the lungs, relieve the hypoxic condition of AECOPD patients, enhance pulmonary function and improve the quality of life of patients.