论文部分内容阅读
复发性呼吸道乳头状瘤是临床上一类由HPV引起的非普通型呼吸道上皮病变．它与生殖器湿疣有共同的病毒病因源，并很大可能是在出生时（少年始发型RRP）或通过密切的性接触（成人始发型RRP）而感染。虽然可进行显微外科激光治疗，但那些具有RRP的患者（无论是成人还是小儿），仍有很大比例的人需反复多次手术，以解决声嘶及上呼吸道阻塞之苦．一些辅助因子的功效（干扰素为首选）还需在病人中进行临床试验调查。在高危险系数孕妇中采用剖腹产分娩具有预防潜在性乳头状癌发生的意义。
Recurrent respiratory papillomatosis is a clinical category of non-ordinary respiratory tract epithelial lesions caused by HPV. It shares a common source of viral etiology with genital warts and is most likely infected at birth (juvenile primary RRP) or by close sexual contact (adult-onset RRP). Although microsurgical laser treatment is available, a significant proportion of those with RRP (both adults and children) require multiple surgeries to resolve hoarseness and upper airway obstruction. The efficacy of some cofactors (interferon is the first choice) requires a clinical trial in the patient. The use of caesarean section delivery in pregnant women with high risk factors has the potential to prevent the occurrence of potential papillary carcinoma.