论文部分内容阅读
目的分析盐酸坦索罗辛和硝苯地平与双氯芬酸钠联合用药治疗输尿管结石引起肾绞痛的疗效。方法365例输尿管结石肾绞痛患者随机分为两组。观察组应用坦索罗辛0.4mg口服,硝苯地平片10mg舌下含服,加双氯芬酸钠50mg口服益;对照组患者用阿托品0.5mg加哌替啶50～100mg肌内注射,两组均常规输液。分别在3O、60、120min及4h观察患者镇痛效果。结果用药后30min及60min时,观察组分别有93、44例有效,对照组分别有109、46例有效,两组比较差异无统计学意义(P>0.05)。但于用药后120min时,观察组173例有效,对照组152例有效;在4h内完全缓解者观察组有162例,对照组有121例;复查B超,观察组共63例结石排出,而对照组只有26例结石排出。两组相比差异均有统计学意义(P<0.001)。结论坦索罗辛、硝苯地平片加双氯酚酸钠组对肾绞痛缓解有效率明显优于阿托品、哌替啶组,其不良反应少,不受麻醉药品限制,还明显有利于结石的排出。
Objective To analyze the curative effect of tamsulosin hydrochloride and nifedipine in combination with diclofenac sodium on renal colic induced by ureteral calculi. Methods 365 patients with ureteral calculi and renal colic were randomly divided into two groups. The observation group was given tamsulosin 0.4mg orally, nifedipine tablets 10mg sublingual, plus diclofenac sodium 50mg oral benefits; control group patients with atropine 0.5mg plus pethidine 50 ~ 100mg intramuscular injection, both conventional Infusion. The analgesic effect was observed at 3O, 60, 120min and 4h respectively. Results At 30 minutes and 60 minutes after treatment, 93 and 44 cases were observed in the observation group and 109 and 46 cases in the control group, respectively. There was no significant difference between the two groups (P> 0.05). However, at 120min after treatment, 173 cases were effective in the observation group and 152 cases in the control group. In the 4h group, there were 162 cases in the observation group and 121 cases in the control group. Control group, only 26 cases of stone discharge. The differences between the two groups were statistically significant (P <0.001). Conclusion The tamsulosin and nifedipine tablets plus diclofenac sodium group are superior to atropine and pethidine group in relieving renal colic. The adverse reactions are less and are not limited by narcotic drugs. They are also obviously beneficial to stones The discharge.