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目的探讨妊娠晚期妇女B族链球菌(group B streptococcus,GBS)带菌情况与母婴预后的关系。方法回顾性分析2013年1月至2014年9月在中山市博爱医院妇产科住院的2 800例妊娠晚期孕妇的临床资料,筛选出其中泌尿生殖道B族溶血性链球菌检测为阳性的160例孕妇为观察组,选取160例阴性结果孕妇为对照组,比较两组母婴预后状况。结果 160例阳性患者均出现相应的临床症状,经治疗后118例治愈,治愈率达73.75%。治疗后发病57例,发病率为35.63%。观察组羊水污染率、新生儿感染率及宫内感染率均高于对照组(P<0.05);观察组剖宫产率高于对照组(P<0.05)。结论妊娠晚期阴道及泌尿系统携带有B族溶血性链球菌,可增加宫内感染、羊水污染、胎儿宫内窘迫、新生儿感染率,并可增加剖宫产率。
Objective To investigate the relationship between the carrier status of group B streptococcus (GBS) and maternal and infant prognosis in the third trimester of pregnancy. Methods The clinical data of 2 800 pregnant women who were hospitalized in the Department of Obstetrics and Gynecology of Pok Oi Hospital of Zhongshan City from January 2013 to September 2014 were retrospectively analyzed. The results showed that genitourinary tract B hemolytic streptococcus was detected as positive Cases of pregnant women as the observation group, select 160 cases of negative pregnant women as control group, comparing the two groups of maternal and infant prognosis. Results 160 cases of positive patients showed the corresponding clinical symptoms, 118 cases cured after treatment, the cure rate was 73.75%. The incidence of 57 cases after treatment, the incidence was 35.63%. The rates of amniotic fluid contamination, neonatal infection and intrauterine infection in observation group were higher than those in control group (P <0.05). The cesarean section rate in observation group was higher than that in control group (P <0.05). Conclusion In the third trimester of pregnancy, vaginal and urinary system can carry streptococcus mutans B, which can increase intrauterine infection, amniotic fluid contamination, fetal distress and neonatal infection, and increase cesarean section rate.