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目的通过对广州市海珠区流动人口肺结核流行因素分析,研究本地区该人群的结核病流行特征,为制定流动人口结核病控制措施提供科学依据。方法登记调查并检测广州市海珠区2005-2006年流动人口和本地人口肺结核患者病例,采用SPSS 13.0软件对原始资料进行统计分析,并计算流行因素的比值比(OR)、95%可信区间(CI)、概率(P)及进行χ2检验、多因素Logistic非参数回归分析。结果流动人口活动性肺结核病有1 112例,男女性别比例为2.0∶1;平均年龄(30.5±18.6)岁;25～岁年龄组占43.1%(OR=3.66、95%CI为2.95～4.54),是罹患结核病的高危年龄组。在初治病人中,流动人口涂阳率比本地人口涂阳率约高5%,二者差异有统计学意义(P=0.047)。多因素Logistic非参数回归分析显示年龄是结核病流行的影响因素。结论应加强对流动人口结核病疫情监控,尤其是流动人口25～岁组对肺结核流行起主要作用。流动人口结核菌涂阳病人是海珠区结核病传播的主要传染源。
Objective To analyze the prevalence of tuberculosis among floating population in Haizhu district of Guangzhou and to provide a scientific basis for the development of control measures for tuberculosis in floating population in this area. Methods The cases of pulmonary tuberculosis among floating population and local population from 2005 to 2006 in Haizhu District of Guangzhou City were enrolled in this study. SPSS 13.0 software was used to analyze the original data and calculate odds ratio (OR), 95% confidence interval CI), probability (P), and Chi-square test, multivariate Logistic nonparametric regression analysis. Results A total of 1 112 cases of migrant pulmonary tuberculosis (TB) were found. The average sex ratio was 2.0:1. The mean age was (30.5 ± 18.6) years old. The age group of 25 ~ 43.1% (OR = 3.66, 95% CI 2.95-4.54) , Is a high-risk age group suffering from tuberculosis. Among newly diagnosed patients, the smear positive rate of floating population was 5% higher than that of the local population, the difference was statistically significant (P = 0.047). Multivariate logistic regression analysis showed that age was the influencing factor of tuberculosis prevalence. Conclusion It is necessary to strengthen the monitoring of epidemic situation of TB in floating population, especially the floating population of 25 ~ age group plays a major role in the tuberculosis epidemic. Floating population of tuberculosis smear-positive patients is the main source of transmission of tuberculosis in Haizhu District.