心肌的机能降低是很重要的,但很少被认为是脓毒性休克的一部分,本文研究了脓毒性休克有关的形态学和生物学异常。心肌细胞在正常环境中孵育,而脓毒性血浆在营养物、氧、pH、电解质及温度所控制的环境中孵育。在孵育结束做了电子显微镜研究,结果,培养基中脓毒性血浆LDH和肌酸激酶水平增高,而脓毒性血浆cAMP水平显著地降低。脓毒性细胞无规律地搏动,并与显示异常的电子显微镜结构共同受到抑制。肌心机能障碍的发生不取决于在实验室控制以前假定的原因,因此,可能是由于内源性 Myocardial dysfunction is important, but seldom considered part of septic shock, this article examines the morphological and biological abnormalities associated with septic shock. Cardiomyocytes are incubated in the normal environment while septic plasma is incubated in an environment controlled by nutrients, oxygen, pH, electrolytes and temperature. Electron microscopy studies were done at the end of incubation, with the result that the levels of septic plasma LDH and creatine kinase increased in the culture medium, while the levels of cAMP in septic plasma were significantly reduced. Septic cells beat irregularly and are co-inhibited with abnormal electron microscopy structures. The onset of myofascial dysfunction does not depend on what was assumed before in laboratory control and therefore may be due to endogenous