习惯性大量饮酒多引起多发性神经元脂肪浸润、小脑变性等神经损害。此外 ,还常见脑萎缩、记忆力低下、脊髓病及植物神经损害等。在 Marchiafava- Bignami病所见的胼胝体脱髓鞘坏死 ,在非 Marchiafava-Bignami病的习惯性大量饮酒者也可见胼胝体萎缩。虽习惯性大量饮酒者可发生脑 Habitual heavy drinking caused by multiple neuronal fat infiltration, cerebellar degeneration and other nerve damage. In addition, common brain atrophy, poor memory, myelopathy and autonomic nerve damage. Demyelination necrosis of the corpus callosum seen in Marchiafava-Bignami disease, corpus callosum atrophy also seen in habitually drinkers who are not in the Marchiafava-Bignami disease. Although habitual heavy drinkers can occur brain