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目的了解西安市男男性行为者(MSM)艾滋病病毒(HIV)感染情况,估算该人群中的HIV新发感染率。方法 2013-2015年通过四轮横断面调查,对2441例MSM进行问卷调查及血清学检测,对HIV阳性的样本,再进行BED HIV-1IgG捕获酶免疫法(BED-CEIA)检测,以此估算该人群的新发感染率。结果 2441例MSM的平均年龄为(28.95±7.52)岁(16~70岁);未婚占69.8%,汉族占99.2%,陕西省户籍占84.2%,在当地居住时间2年以上占81.3%,文化程度大专及以上占78.1%,认为自己是同性恋的占73.4%,最主要交友场所为网络/交友软件的占83.6%,艾滋病知识知晓率为85.8%。共筛查出HIV阳性179例,筛查阳性率7.33%,接受BED检测的158例样本中,71例为新近感染,四轮调查的新发感染率分别为7.20%[95%可信区间(CI):3.41%~10.99%]、9.18%(95%CI:5.06%~13.31%)、6.85%(95%CI:3.09%~10.60%)、4.88%(95%CI:1.84%~7.92%),合计新发感染率为7.00%(95%CI:5.11%~8.90%)。近六个月与临时性伴发生同性性行为是否使用安全套、近六个月是否使用如RUSH的助性剂、近一年是否接受过HIV检测、梅毒检测结果4个因素,对MSM新近感染HIV有统计意义(P<0.05)。结论西安市艾滋病防治各种干预检测工作对疫情的控制是有效的,但仍需继续加强干预检测力度,遏制艾滋病疫情向一般人群的蔓延。
Objective To understand the HIV status of MSM in Xi’an and to estimate the prevalence of HIV infection in this population. Methods A total of 2441 MSM were surveyed and serologically tested with four rounds of cross-sectional survey from 2013 to 2015. The HIV-positive samples were tested by BED HIV-1 IgG capture enzyme immunoassay (BED-CEIA) The new infection rate in this population. Results The average age of 2441 MSM was (28.95 ± 7.52) years old (16 ~ 70 years). Unmarried 69.8%, Han 99.2%, Shaanxi 84.2%, living in the area for more than 2 years 81.3% The degree of college and above accounted for 78.1%, accounting for 73.4% of them being homosexual, the most important places for making friends were network / friends software, accounting for 83.6% and AIDS awareness rate was 85.8%. A total of 179 HIV positive cases were screened out, with a positive screening rate of 7.33%. Among the 158 samples tested by BED, 71 were newly infected and the new infections in four rounds were 7.20% [95% confidence interval (95% CI: 3.06% to 13.31%), 6.85% (95% CI: 3.09% to 10.60%) and 4.88% (95% CI: 1.84% to 7.92% ), The total new infection rate was 7.00% (95% CI: 5.11% ~ 8.90%). Whether the use of condoms during the past six months and having sex with a temporary partner, whether to use a RUSH adjuvant in the past six months, whether the HIV test has been conducted in the past year and the result of syphilis test, There was statistical significance (P <0.05). Conclusion It is effective to control the epidemic situation in all kinds of interventions in AIDS prevention and control in Xi’an. However, it is still necessary to continue to strengthen the intervention testing to curb the spread of AIDS epidemic to the general population.