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1986～1989年,我科经病原学检查确诊的巨细胞病毒感染者28例,现将临床观察及中西医结合治疗结果报道如下。临床资料 28例中男16例,女12例,年龄最小24天,最大3个月。起病时间最短生后3天,最长生后2个月。患儿足月产19例、早产9例。全部病例均以黄疸为主诉起病,均有肝大,最小助下2cm,最大6cm;腹泻25例(89.2％),呕吐20例(78.5％),白便21例(75％),脾大19例(67.8％),腹胀18例(69.8％)。合并先天性佝偻病者24例(85％),合并肺炎者15例,合并晚发性维生素K缺乏颅内出血者2例。肝功有改变者23例(82.1％),全部病例谷丙转氨酶升高;CMV—IgM抗体升高者18例(64.5％);尿中查到巨细胞包涵体者8例(28.5％)。死后病理证实者2例。按中医辨证属阴黄者22例(78.5％),阳黄者6例(11.5％)。
1986 to 1989, our department diagnosed by etiological examination of cytomegalovirus in 28 patients, now clinical observation and Integrative Medicine results reported below. Clinical data of 28 cases, 16 males and 12 females, the youngest 24 days, up to 3 months. The shortest onset time after 3 days, the longest after 2 months. 19 cases of full-term children with preterm delivery in 9 cases. All cases were jaundice-based complaints of onset, both liver, the smallest help 2cm, maximum 6cm; diarrhea in 25 cases (89.2%), vomiting in 20 cases (78.5%), white in 21 cases (75% 19 cases (67.8%), abdominal distension in 18 cases (69.8%). Twenty-four patients (85%) had congenital rickets, 15 patients had pneumonia, and 2 patients had delayed onset vitamin K deficiency due to intracranial hemorrhage. Twenty-three patients (82.1%) had changes in liver function, all patients had elevated alanine aminotransferase (ALT), 18 patients (64.5%) had elevated CMV-IgM antibody, and 8 patients (28.5%) found macrophage inclusion in urine. Postmortem pathology confirmed in 2 cases. According to TCM is a shade of Yin in 22 cases (78.5%), Yang yellow in 6 cases (11.5%).