许多药物在胃肠道的水性溶液中很难溶解,在体内的溶出速率低,故吸收不完全且无规律。一般减小药物的粒径能增加溶出速率。在吸收过程主要取决于溶出速率的情况下,药物的表面积增大,溶出速率便增加,吸 Many drugs in the gastrointestinal tract aqueous solution is difficult to dissolve in vivo dissolution rate is low, so the absorption is incomplete and irregular. Generally reduce the drug particle size can increase the dissolution rate. In the case that the absorption process mainly depends on the dissolution rate, the surface area of ​​the drug increases, the dissolution rate increases, and the absorption