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为评价头颈部鳞状细胞癌单纯放疗或与手术联合治疗加用丝裂霉素C的作用,作者在1980~1986年间作了前瞻性随机临床试验。可评价的患者共117例,其中男95例,女22例,年龄31~77岁,平均57岁。肿瘤部位;口腔26例,口咽30例,下咽23例,喉29例,鼻咽9例。将以上患者随机分为两组,放疗组61例,放疗加丝裂霉素C组56例。两组患者的性别,年龄、肿瘤部位、TNM分期等基本一致。
In order to evaluate the effect of mitomycin C plus radiotherapy alone or combined with surgery on head and neck squamous cell carcinoma, the authors performed a prospective randomized clinical trial between 1980 and 1986. A total of 117 patients were evaluable, including 95 males and 22 females, aged 31-77 years with an average age of 57 years. Tumor site; 26 cases of oral cavity, 30 cases of oropharynx, 23 cases of hypopharynx, 29 cases of larynx, 9 cases of nasopharyngeal. The above patients were randomly divided into two groups, radiation therapy group 61 cases, radiotherapy and mitomycin C group 56 cases. The gender, age, tumor site, and TNM staging were basically the same in both groups.