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目的:评价氧氟沙星和头孢曲松与氨溴索联用对老年患者糖尿病伴肺炎的临床疗效。方法:选取2013年6月—2015年12月期间收治的老年糖尿病伴肺炎患者86例,采用随机数字表法将其分为观察组和对照组,每组43例;对照组患者给予氧氟沙星和头孢曲松治疗,观察组患者在对照组治疗基础上给予氨溴索治疗,比较两组患者治疗后的总有效率,以及发热、咳嗽临床症状评分值和不良反应的发生率。结果:观察组患者治疗后的总有效率为86.05%高于对照组为72.09%(P<0.05);治疗后,两组患者的发热评分值0,2和3分的比例明显优于治疗前(P<0.05),发热评分值为0,1和2分的比例明显优于对照组(P<0.05);两组患者咳嗽评分值为0和3分的比例优于治疗前(P<0.05),观察组患者的咳嗽评分值为0,1和2分的比例优于对照组(P<0.05);两组患者用药期间均未发生不良反应。结论:氧氟沙星和头孢曲松与氨溴索联用治疗老年患者糖尿病伴肺炎的临床疗效优于氧氟沙星和头孢曲松的治疗,发热、咳嗽症状明显改善,且未见不良反应的发生。
Objective: To evaluate the clinical efficacy of ofloxacin and ceftriaxone in combination with ambroxol on diabetic patients with pneumonia in elderly patients. Methods: Totally 86 elderly patients with diabetes mellitus and pneumonia were selected from June 2013 to December 2015. They were divided into observation group and control group with 43 cases in each group by random number table. Patients in the control group were treated with ofloxacin Star and ceftriaxone. Patients in the observation group were treated with ambroxol on the basis of the control group. The total effective rate and the clinical symptom score of cough and the incidence of adverse reactions were compared between the two groups. Results: After treatment, the total effective rate of the observation group was 86.05%, which was significantly higher than that of the control group (72.09%, P <0.05). After treatment, the scores of fever scores of 0, 2 and 3 in the two groups were significantly better than those before treatment (P <0.05). The ratio of fever score of 0, 1 and 2 was significantly better than that of the control group (P <0.05). The scores of cough score 0 and 3 in both groups were better than those before treatment (P <0.05) ). The cough score of the observation group was 0, 1 and 2, which was better than that of the control group (P <0.05). No adverse reactions occurred in both groups during the medication. Conclusion: The efficacy of ofloxacin and ceftriaxone in combination with ambroxol in the treatment of diabetic patients with pneumonia in elderly patients is better than that of ofloxacin and ceftriaxone treatment. The symptoms of fever and cough are obviously improved with no adverse reaction happened.