患者,男,13岁,因尿道下裂就诊。系第2胎,足月顺产,出生体重2kg。出生时父25岁、母22岁。母在孕期无患病及服药史。父母非近亲婚配,均体健。有1妹表型正常,1兄生后7天抽风死亡。患儿自幼生长发育迟缓、身高低于同龄儿,但智力正常。 Patient, male, 13 years old, was diagnosed with hypospadias. Department of the second child, full-term natural delivery, birth weight 2kg. Father 25 years old at birth, mother 22 years old. Mother during pregnancy without illness and medication history. Parents non-relatives marriage, are physical health. A sister phenotype normal, 1 brother died after 7 days of ventilation. Childhood growth retardation, height below age, but normal intelligence.