应用心得安治疗心绞痛及心律失常的趋势正在增加。然而,心得安用于哮喘患者则明显地增加呼吸道阻力,其他可应用的肾上腺素β受体阻滞剂或缺乏心脏选择性,或具有直接抑制心肌的作用,或具有内源性拟交感神经作用,因而使之不大适于治疗冠状动脉疾病的患者。Tolamolol为一种对心脏有选择性的肾上腺素β受体阻滞剂,它并无直接抑制心肌细胞膜作用,也无内源性拟交感神经作用为了评定tolamolol与心得安在呼吸道动力学上的作用作一比较,作者研究了15名患轻度至中度哮喘病 Application of the safety of angina and arrhythmia treatment trend is increasing. However, propranolol used in patients with asthma significantly increased airway resistance, other available adrenergic β-blockers or lack of cardiac selectivity, or direct myocardial inhibition, or have an endogenous sympathetic effect , Making it less suitable for the treatment of coronary artery disease in patients. Tolamolol is a cardiac selective adrenergic beta-blocker that does not directly inhibit myocardial cell membrane effects nor endogenous sympathomimetic effects. In order to assess the effects of tolamolol and propranolol on respiratory kinetics For comparison, the authors studied 15 patients with mild to moderate asthma