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[目的]观察调脂通脉汤联合拜阿司匹灵与阿托伐他汀钙治疗冠心病不稳定型心绞痛疗效。[方法]使用多中心随机平行对照方法,将60例住院患者按病志号抽签方法简单随机分两组。对照组30例拜阿司匹灵,100mg/次,1次/d;阿托伐他汀钙,20mg/次,1次/d。治疗组30例调脂通脉汤(红花15g,桃仁、当归各10g,赤、白芍各15g,丹参20g,川芎、郁金、香附各15g,佛手6g,枳壳、人参各10g,炒决明子15g,制黄精20g,生山楂20g,全瓜蒌30g,陈皮、泽泻各15g,炙甘草6g;心肾阳虚加炮附子先煎30g,仙灵脾、桂枝各20g,车前子15g,茯苓30g;气阴两虚重用人参,加黄芪30g,二冬各15g;痰湿较重加半夏12g,茯苓、苍术各15g,通草12g,肉蔻15g),1剂/d,水煎400m L,早晚口服;西药治疗同对照组。连续治疗3个月为1疗程。观测临床症状、冠状动脉狭窄程度、不良反应。连续治疗2疗程,判定疗效。[结果]心绞痛疗效、CCTA疗效治疗组均优于对照组(P<0.05)。[结论]调脂通脉汤联合拜阿司匹灵与阿托伐他汀钙治疗冠心病不稳定型心绞痛,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the therapeutic effect of Tiaozhi Tongmai Decoction combined with aspirin and atorvastatin calcium on unstable angina pectoris. [Methods] Sixty patients were randomly divided into two groups randomly according to the method of lot drawing by using the method of multi-center randomized parallel control. The control group, 30 cases of aspirin, 100mg / time, 1 / d; atorvastatin calcium, 20mg / time, 1 / d. The treatment group, 30 cases of Tiaozhi Tongmai soup (saffron 15g, peach kernel, angelica 10g, red, white peony root of 15g, Salvia 20g, Chuanxiong, turmeric, Cyperus rotundus 15g, bergamot 6g, Citrus aurantium, Fried Cassia 15g, Polygonatum 20g, raw Hawthorn 20g, whole melon 蒌 30g, dried tangerine peel, Alisma 15g, Baked Licorice 6g; Heart and Kidney plus cannon aconite first fried 30g, Epimedium, cassia 20g, car Zi 15g, Poria 30g; Qi and Yin weight ginseng, plus Astragalus 30g, two winter 15g; phlegm heavier Pinellia 12g, Poria, Atractylodes each 15g, through grass 12g, nutmeg 15g), 1 / Decoction 400m L, morning and evening oral; western medicine treatment with the control group. Continuous treatment of 3 months for a course of treatment. Clinical symptoms, coronary stenosis and adverse reactions were observed. Continuous treatment of 2 courses to determine the efficacy. [Results] The efficacy of angina pectoris in CCTA group was better than that in control group (P <0.05). [Conclusion] Tiaozhi Tongmai Decoction combined with aspirin and atorvastatin calcium can treat unstable angina pectoris of coronary heart disease, with satisfactory curative effect and no serious adverse reactions. It is worth popularizing.