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近年来研究发现,胰岛素抵抗作为许多临床疾病联系的纽带和基础,在诸多心血管疾病乃至心力衰竭的发生、发展过程中起着相当重要的作用。而脂肪组织分泌的脂肪细胞因子在胰岛素抵抗及心血管疾病的病理生理过程中扮演重要角色。随着对脂肪细胞因子了解的深入,逐步认识到其可能是胰岛素抵抗和心血管疾病的中间环节。本文重点阐述脂肪细胞因子与胰岛素抵抗及慢性心力衰竭的关系,并希望在多种心血管疾病和心力衰竭的临床治疗过程中起到一些指导作用。
In recent years, the study found that insulin resistance as a link between many clinical diseases and foundation, in many cardiovascular diseases and even heart failure occurrence and development play a very important role. Adipocyte-secreting adipocytes play an important role in the pathophysiology of insulin resistance and cardiovascular disease. With the deep understanding of adipocytokines, it is gradually realized that it may be an intermediate link between insulin resistance and cardiovascular diseases. This article focuses on the relationship between adipocytokines and insulin resistance and chronic heart failure and hopes to play a guiding role in the clinical management of many cardiovascular diseases and heart failure.