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临床资料证实月经过多和经间出血是放置 IUD 者中断使用的主要原因。带器者经血量测定表明经血量增加约为50～100%,更重要的是导致缺铁性贫血者占30～50%。虽然 IUD 合并子宫出血临床报导较;多,但实验室方面探讨其原因者却很少。光镜观察带器者宫内膜组织改变,多未涉及出血原因和血管系统变化,应用透射电镜观察IUD 影响,大多集中在宫内膜腺体和间质,述及血管者更廖廖无几。本文拟对带器妇女子宫内膜血管损伤超微结构研究工作的进展作一简要综述,从而探索其出血机理,并为防治提供形态学依据。
Clinical data confirmed that menorrhagia and intercostal bleeding is the main reason for the interruption of the use of IUD placement. Blood tests with a device that menstrual blood volume increased by about 50 to 100%, more importantly, lead to iron deficiency anemia accounted for 30 to 50%. Although IUD combined with clinical reports of uterine bleeding; more, but the laboratory to explore its reasons are few. Light microscope observation with endometrial tissue changes, mostly not involved in bleeding causes and changes in the vascular system, the application of transmission electron microscopy IUD impact, mostly in the endometrial glands and stroma, involving more or less blood vessels. This article intends to summarize the progress of research on the ultrastructure of endometrial vascular injury in women with devices, so as to explore its bleeding mechanism and provide morphological evidence for prevention and treatment.