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The karst groundwater system is extremely vulnerable and easily contaminated by human activities.To understand the spatial distribution of contaminants in the groundwater of karst urban areas and contributors to the contamination,this paper employs the spatial information statistics analysis theory and method to analyze the karst groundwater environment in Guiyang City,Based on the karst groundwater quality data detected in 61 detection points of the research area in the last three years,we made Kriging evaluation isoline map with some ions in the karst groundwater,such as SO42,Fe3+,Mn2+ and F,analyzed and evaluated the spatial distribution,extension and variation of four types of ions on the basis of this isoline map.The results of the analysis show that the anomaly areas of SO42-,Fe3+,Mn2+,F and other ions are mainly located in Babaao,Mawangmiao and Sanqiao in northwestern Guiyang City as well as in its downtown area by reasons of the original non-point source pollution and the contamination caused by human activities (industrial and domestic pollution).