肺癌早期转移是肺癌的恶性标志和特征,也是肺癌患者治疗失败和死亡的主要原因,所以研究肺癌的早期转移已成为当今的研究热点。肺癌的转移是宿主与肿瘤细胞相互作用的一个复杂、多步骤的过程,受不同的基因组的控调。近年来通过分子克隆技术发现一类参与调控肿瘤转移的基因。由于 Early metastasis of lung cancer is a malignant sign and characteristic of lung cancer, which is also the main reason of failure and death of lung cancer patients. Therefore, studying the early metastasis of lung cancer has become a hot research topic nowadays. Lung cancer metastasis is a complex, multi-step process of host-tumor cell interaction regulated by different genomes. In recent years, through molecular cloning technology found a class of genes involved in the regulation of tumor metastasis. due to