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目的探讨全麻下全肺灌洗治疗疗效。方法回顾性分析8例肺泡蛋白沉着症患者。结果 8例患者,男性4例,平均年龄44.4岁。8例均在全麻下行全肺灌洗治疗,7例分别进行了双肺灌洗87.5%(7/8),1例单侧肺灌洗12.5%(1/8)。术后咳嗽、肺部湿啰音25%(2/8),术后发热12.5%(1/8),术中出现哮鸣音12.5%(1/8)。术后咳嗽、气短明显改善100%(8/8),紫钳有所改善100%(8/8)。动脉血氧分压、血氧饱和度、弥散功能均有提高改善100%(8/8)。肺部影像学改善75%(6/8)。结论全麻下全肺灌洗治疗是目前治疗肺泡蛋白沉着症的最有效的方法。
Objective To investigate the effect of whole lung lavage in general anesthesia. Methods Retrospective analysis of 8 patients with pulmonary alveolar proteinosis. Results 8 patients, 4 males, mean age 44.4 years old. Eight patients underwent whole-lung lavage under general anesthesia. Seven patients underwent bilateral lavage of 87.5% (7/8) and one of unilateral lung lavage of 12.5% (1/8), respectively. Postoperative cough, pulmonary rales 25% (2/8), postoperative fever 12.5% (1/8), intraoperative wheezing 12.5% (1/8). Postoperative cough, shortness of breath improved significantly by 100% (8/8), and redcaps improved by 100% (8/8). Arterial oxygen partial pressure, oxygen saturation, diffuse function improved 100% (8/8). Pulmonary imaging improved by 75% (6/8). Conclusion The whole lung lavage treatment under general anesthesia is the most effective method for the treatment of pulmonary alveolar proteinosis.