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目的研究肿瘤相关物质(TSGF)在白血病、淋巴瘤的诊断及预后判断中的作用。方法对白血病、淋巴瘤患者分别测定治疗前后的血清TSGF水平,以健康者血清TSGF水平作为对照。结果白血病、淋巴瘤患者血清TSGF水平显著高于健康者(F=11.32,P<0.01),经治疗后完全缓解者血清TSGF水平显著下降,而未完全缓解者无明显变化。结论血清TSGF水平是诊断白血病、淋巴瘤的有效指标,并可作为判断预后及治疗效果的辅助指标。
Objective To study the role of tumor-associated substances (TSGF) in the diagnosis and prognosis of leukemias and lymphomas. Methods Serum levels of TSGF were measured in patients with leukemia and lymphoma before and after treatment, respectively. Serum levels of TSGF were used as controls. Results Serum TSGF levels in patients with leukemia and lymphoma were significantly higher than those in healthy controls (F = 11.32, P <0.01). Serum levels of TSGF were significantly decreased in patients with complete remission after treatment, but not in those without complete remission. Conclusions The level of serum TSGF is an effective index for the diagnosis of leukemia and lymphoma, and can be used as an auxiliary index to judge prognosis and treatment effect.