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高脂血症引发的炎性反应、氧化应激、脑β淀粉样蛋白沉积等对脑组织造成损伤,通过神经递质产生(抑制)兴奋、影响Ca2+平衡等多种方式介导损伤(抗损伤)效应.本文就近年的相关报道对高脂血症与脑损伤、脑神经递质进行综述.“,”Hyperlipidemia can damage the brain tissue,by stimulating inflammatory response,enhancing oxidative stress damage and inducting the deposition of amyloid in the brain.It can also interfere with the effect of injury (anti-injury) by generating (inhibiting) excitability of neurotransmitter and interfering with the balance of the Ca2+.This review discusses the relationship between hyperlipidemia,brain damage and neurotransmitters according to the recent reports.