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巯甲丙脯酸(CPT)作为一种新型的扩血管药,可有效地治疗高血压和心力衰竭。CPT 可影响内环境的稳定,特别是对钾代谢。我们遇到1例肺心病心衰病人联用 CPT、氨苯喋啶致高血钾、窦室传导,现报告如下。病历摘要男患,66岁,因反复咳嗽,气急3年,浮肿8天入院。查体;体温37.3℃,脉搏108次/分,血压14.0/8.66kPa,呼吸24次/分。口唇发绀,颈静脉怒张,桶状胸。心率108次/分,律齐,无杂音,两肺可闻及哮鸣音。肝肋下1.5cm,质中,有压痛,肝颈返流征(+),两下肢重度凹陷性水肿。肝肾功能正常,血钾3.5mmol/L。心电图示窦性心动过速,T_(1、avR)、V_6低平
Captopril (CPT), a new vasodilator, is effective in the treatment of hypertension and heart failure. CPT can affect the stability of the internal environment, especially for potassium metabolism. We encountered a case of heart failure in patients with pulmonary heart disease CPT, methotrexate induced hyperkalemia, sinus conduction, are as follows. Medical history male suffering, 66 years old, due to repeated cough, shortness of breath 3 years, edema admitted to hospital for 8 days. Physical examination; body temperature 37.3 ℃, pulse 108 beats / min, blood pressure 14.0 / 8.66kPa, breathing 24 beats / min. Cyanosis lips, jugular vein engorgement, barrel chest. Heart rate 108 beats / min, law Qi, no noise, both lungs can smell and wheeze. Liver ribs 1.5cm, quality, tenderness, liver reflux syndrome (+), two lower limb severe pitting edema. Liver and kidney function is normal, serum potassium 3.5mmol / L. Electrocardiogram shows sinus tachycardia, T_ (1, avR), V_6 low flat