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自从 Hargraves 发现红斑狼疮(LE)细胞以来,在 SLE 诊断上是具有高度诊断价值的。通常红斑狼疮细胞是试管内所见到的现象,很少在体内见到。多见于患者滑囊液、胸水、心包液、腹水、脑脊液等体腔液中,有时可见于末期患者的骨髓,末稍血的直接的涂抹标本上。而在试管内发现的红斑狼疮小体与组织内相应的苏木紫小体,主要见于剖检材料。对 S.L.E.死后诊断是有价值的,但皮疹的活检很少见到。
Since Hargraves discovered lupus erythematosus (LE) cells, diagnosis of SLE is of high diagnostic value. Often lupus erythematosus cells are seen inside the test tube and are rarely seen in the body. More common in patients with synovial fluid, pleural effusion, pericardial fluid, ascites, cerebrospinal fluid and other body cavity fluid, and sometimes can be seen in the end of the patient’s bone marrow, the end of the blood smear specimens directly. However, the lupus erythematosus found in the test tube and the corresponding hematoxylin-eosin in the tissue were mainly found in the autopsy materials. Post-mortem diagnosis of S.L.E. is valuable, but rare rash biopsies are seen.