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报告1例鼻部血管球瘤患者女,56岁。鼻尖部红色结节1年,无自觉症状。皮损组织病理学检查示:肿瘤细胞体积小,形态圆形、大小一致,胞质嗜酸性,细胞无明显异形性及核分裂象。肿瘤血管丰富,瘤细胞簇状围绕于血管周,间质可见黏液沉积,可见成纤维细胞增生。免疫组化示:波形蛋白(vimentin)(++)、平滑肌肌动蛋白(SMA)(+++)、阿辛蓝染色均为阳性,中央血管内皮细胞CD31(+),神经纤维S-100蛋白散在阳性。结合临床诊断为:血管球瘤。
Report of 1 cases of nasal glomus tumor Female, 56 years old. Nose tip red nodules 1 year, no symptoms. Histopathological examination revealed that the tumor cells were small in size, circular in shape, consistent in size, eosinophilic cytoplasm, with no obvious atypia of cells and mitotic figures. Rich tumor blood vessels, tumor cells clustered around the perivascular, interstitial mucus deposition seen, we can see fibroblasts proliferation. Immunohistochemistry showed that vimentin (++), smooth muscle actin (+++) and Alcian blue staining were all positive. CD31 (+) of central vascular endothelial cells, S-100 Protein scattered positive. Combined with clinical diagnosis: glomus tumor.